The 2013 edition of The Sanford Guide to HIV/AIDS Therapy reflects the continuing evolution of HIV from epidemic to manageable chronic disease, at least in parts of the world with access to the latest antiretroviral drugs. New agents, such as rilpivirine, new combination ARV drug formulations, such as Stribild, and new guidelines on pre-exposure prophylaxis (PrEP) are included. ART recommendations have been updated in accordance with the most recent sets of guidelines and the section on HIV diagnostics have been revised to include newly available tests. We have undertaken a major revision of the sections on complication of ART and AIDS-related complications and opportunistic infections to reflect the changing understanding and management of HIV. In the previous edition, we expanded our focus to include a new section on Hepatitis C virus (HCV) infections. With this edition, we significantly expand our coverage of diagnosis and treatment of Hepatitis B virus infections. In many ways, the
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